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4A molecular sieve, a zeolite with 4A pore size, is vital in industrial gas separation, air drying, and solvent purification for its high adsorption capacity. However, impurity content directly impacts its efficiency and lifespan. This article explores impurity sources, detection, and control in 4A molecular sieve. Common impurities include water, CO₂, organic compounds, and metal ions (e.g., Na⁺, K⁺). Water enters during synthesis/post-treatment, reducing adsorption; CO₂ and organics stem from raw material impurities or incomplete crystallization. Metal ions affect stability and selectivity. To ensure quality, accurate detection is key. Methods like GC (for volatiles), ICP-MS (trace metals), and TGA (water content) are widely used. Controlling impurities involves optimizing synthesis: adjusting SiO₂/Al₂O₃ ratio and reaction temperature promotes complete crystallization, reducing inclusions. Post-treatments like calcination and ion exchange remove adsorbed impurities. In industrial settings, proper packing (e.g., structured packing) and tower internal (e.g., distillation columns) enhance separation, minimizing impurity breakthrough. In summary, managing 4A molecular sieve impurity content is critical. By understanding sources, using advanced detection, and optimizing production with suitable packing and tower internal, its quality and efficiency improve, meeting industrial demands for high-purity separation and drying.